Metribolone, also known as Methyltrienolone, is one of the most powerful and dangerously toxic anabolic steroids ever synthesized. It was never approved for human use and exists purely as a research chemical. Its reputation for extreme hepatotoxicity (liver damage) is unparalleled. This document serves as a stark warning, not a guide. The use of Metribolone in humans is exceptionally dangerous and can lead to rapid and irreversible organ damage, including liver failure.
EXTREME DANGER WARNING: NOT FOR HUMAN USE
Metribolone is not a medication or a supplement; it is a laboratory tool used in scientific research to study the androgen receptor due to its high binding affinity. It was deemed too dangerous for clinical trials in humans. Any source selling this substance for personal use is operating illegally and irresponsibly. Ingesting Metribolone is a direct chemical assault on the liver and can have fatal consequences.
What is Metribolone (Methyltrienolone)?
Metribolone is a C17-alpha alkylated oral anabolic steroid. Structurally, it is a derivative of trenbolone, modified to be orally active. This modification also makes it astoundingly potent and incredibly damaging to the liver. On paper, it has anabolic and androgenic ratings that are thousands of times greater than testosterone, making it one of the most powerful steroids ever created.
Chemical Profile and Research Application
Metribolone’s extreme potency and resistance to being metabolized make it a useful reference compound in laboratory settings for androgen receptor binding assays. Scientists use it as a stable benchmark against which other compounds can be measured. This scientific application is its only legitimate purpose. It was never intended to be consumed.
Why it Was Never Approved for Medical Use
During its initial development and study in the 1960s, it became immediately clear that Metribolone caused severe hepatotoxicity even at minuscule doses. The risk-benefit ratio was so catastrophically poor that all further development for therapeutic use in humans was abandoned.
The Catastrophic Health Consequences of Metribolone
The risks associated with Metribolone cannot be overstated. It is considered by many experts to be the single most dangerous steroid a person could use.
Unparalleled Hepatotoxicity (Liver Damage)
This is the primary and most life-threatening danger.
- Rapid Liver Stress: Even microgram doses, far less than the 1mg mentioned, can cause a dramatic and rapid increase in liver enzymes, signaling severe liver cell distress and damage.
- Cholestasis: It can halt the flow of bile from the liver, leading to jaundice (yellowing of the skin and eyes), intense itching, and a buildup of toxic substances in the blood.
- Peliosis Hepatis & Cancer: Long-term exposure, even at tiny doses, dramatically increases the risk of blood-filled cysts in the liver (peliosis hepatis) and liver cancer.
- Acute Liver Failure: There is a very real risk of complete liver failure, which is a medical emergency with a high mortality rate.
Other Severe Side Effects
Beyond the liver, Metribolone is devastating to the rest of the body.
- Profound Hormonal Shutdown: It will cause an immediate and total shutdown of natural testosterone production, leading to testicular atrophy, infertility, and severe endocrine disruption.
- Extreme Androgenicity: Users can expect the worst possible androgenic side effects: severe cystic acne, rapid and irreversible male pattern baldness, and aggressive body hair growth.
- Cardiovascular Strain: Like other powerful steroids, it will severely damage cholesterol profiles, increasing the risk of heart attack and stroke.
- Mental Effects: Due to its immense androgenic power, it can cause extreme aggression, irritability, anxiety, and paranoia.
- Progestogenic Activity: As a trenbolone derivative, it can exhibit progestogenic activity, which can lead to side effects like gynecomastia that are difficult to manage.
Legal Status: An Unapproved Research Chemical
Metribolone is not a controlled substance in the same way as prescription steroids simply because it has no history of medical use. However, its sale for human consumption is illegal under laws governing unapproved drugs. It exists solely on the black market, where its purity, dosage, and even its actual identity are completely unverified.
Frequently Asked Questions (FAQs) about Metribolone
Is there any way to use Metribolone safely?
- Emphatically, no. There is no dose, cycle length, or protective supplement that can make this substance safe for human use. Its inherent toxicity is too high.
Why is it called “oral Tren”?
It is structurally an orally active form of trenbolone. However, this nickname is dangerously misleading as it dramatically understates Metribolone’s toxicity, which is far greater than that of injectable trenbolone.
What should someone do if they have taken Metribolone?
They should seek medical attention immediately and request a full liver function panel. They must be honest with their doctor about what they have taken. It is critical to cease use instantly and never touch the substance again.
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